Loading clinical trials...

RECRUITINGPhase 2NCT05470777

CD22/CD19 CAR-T and Auto-HSCT Sandwich Strategy as Consolidation Therapy for B-ALL

Chimeric antigen receptor T-cell (CAR-T) therapy has achieved remarkable efficacy in B-cell acute lymphoblastic leukemia (B-ALL). However, relapse after CAR-T has been a major issue. Multi-antigen CAR...

Lead sponsor: The First Affiliated Hospital of Soochow University•1 locations•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Contacts

Sheng-Li Xue, M.D.

CONTACT

+86 512 67781139 slxue@suda.edu.cn

Related studies

RECRUITINGPhase 1/2

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

NCT06395103 · B-cell Acute Lymphoblastic Leukemia, Diffuse Large B-cell Lymphoma, and more

RECRUITINGPhase 1/2

Adaptive Dual-Target CAR-T Cells for Relapsed or Refractory Hematologic Malignancies

NCT07523555 · Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia, Relapsed/Refractory B-cell Non-Hodgkin Lymphoma or CLL/SLL, and more

RECRUITINGPhase 3

A Study of Fludarabine Dosing in Children and Young Adults With B-cell Acute Lymphoblastic Leukemia

NCT07223021 · B-cell Acute Lymphoblastic Leukemia

RECRUITINGPhase 1/2

Co-administration of CART22-65s and huCART19 for B-ALL

NCT05674175 · B-cell Acute Lymphoblastic Leukemia, B Lineage Lymphoblastic Lymphoma

RECRUITINGEARLY Phase 1

Clinical Study of SYNCAR-100 in the Treatment of Relapsed/Refractory Acute B-Lymphoblastic Leukemia

NCT07429461 · B-Cell Acute Lymphoblastic Leukemia

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: June 5, 2025Terms

Trial snapshot

StatusRECRUITING

PhasePHASE2

Enrollment37

Start dateJan 2020

Last updatedJun 5, 2025

Condition

B-cell Acute Lymphoblastic Leukemia

Locations shown

The First Affiliated Hospital of Soochow University

Suzhou, Jiangsu

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 5, 2025Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

CD22/CD19 CAR-T and Auto-HSCT Sandwich Strategy as Consolidation Therapy for B-ALL

What this study is about

Save this trial guide to your notes

Contacts

Sponsors

Related studies

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

Adaptive Dual-Target CAR-T Cells for Relapsed or Refractory Hematologic Malignancies

A Study of Fludarabine Dosing in Children and Young Adults With B-cell Acute Lymphoblastic Leukemia

Co-administration of CART22-65s and huCART19 for B-ALL

Clinical Study of SYNCAR-100 in the Treatment of Relapsed/Refractory Acute B-Lymphoblastic Leukemia

Trial snapshot

Condition

Locations shown

For caregivers