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Effectiveness of a Community Health Worker-Led Low-Sodium Salt Intervention to Reduce Blood Pressure: A Cluster Randomized Controlled Trial in Rural Bangladesh
The sodium found in salt is a powerful cause of high blood pressure, and most sodium ingested by humans is from their diet. High blood pressure is known to cause heart attacks and strokes, so various public health programs have attempted to find ways for people to reduce their salt intake to avoid these complications. These programs, however, have proven challenging, as asking people to alter their food preparation practices is often met with resistance. As such, we wish to test the blood pressure-lowering effects of low sodium salt substitute (LSSS), a salt substance in which a third of the compound by weight is composed of potassium (which does not increase blood pressure) rather than sodium. Additionally, the best way of supplying LSSS to people is yet unknown. We thus propose to study the effectiveness of an LSSS product by directly providing it via community health workers in 309 households in rural Bangladesh.
The overall objective of this study is to assess the effectiveness of providing access to low-sodium salt substitute (LSSS) (a compound in which a percentage of the sodium chloride (NaCl) is replaced by potassium chloride (KCl) for blood pressure (BP) reduction in a general population of adults (aged 18 years and older) in rural Bangladesh. The intervention will be delivered in the study wing by community health workers to determine if this method is an efficacious approach for blood pressure lowering in this setting.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
Yes
BRAC University, James P Grant School of Public Health
Dhaka, Mohakhali, Bangladesh
Start Date
January 26, 2023
Primary Completion Date
May 30, 2024
Completion Date
December 1, 2024
Last Updated
February 17, 2026
618
ACTUAL participants
Low-Sodium Salt Substitute
DIETARY_SUPPLEMENT
Information/Education
BEHAVIORAL
Lead Sponsor
Stanford University
Collaborators
NCT02417740
NCT07482930
Data Source & Attribution
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