PET-study on the Role of the Reward System in Weight Loss After Bariatric Surgery

Exclusion Criteria

• •Presence of a DSM-IV axis 1 disorder
• •The use of drugs that bind to dopamine D2/3 receptors, including various classes of antipsychotics and antidepressants
• •History of stroke, brain tumor, Parkinson's Disease or dementia
• •History of head trauma with loss of consciousness
• •Alcohol or substance abuse in the last 6 months
• •Alcohol consumption 24h prior to PET scanning
• •Smoking or other forms of nicotine intake 12 hours prior to PET scanning
• •Use of anorectic drugs in the last 6 months
• •Current pregnancy
• •Medication for Diabetes Mellitus
• •Claustrophobia
• •The presence of implanted metal objects of the type which may concentrate radiofrequency fields or cause tissue damage from twisting in a magnetic field (such as certain implanted devices, shrapnel, ocular metal shavings)
• •Patients with a bodyweight \> 200kg will be excluded to ensure the maximum load of the camera bed of the PET-scanner (227 kg) is not exceeded.