SGLT2 Inhibitors As First Line Therapy to Prevent Renal Decline in Type 2 Diabetes

Exclusion Criteria

• •Have an immediate need for rapid intensification of glucose lowering therapy due to marked hyperglycaemia; or
• •There is a definite indication for, or contraindication to, either metformin or SGLT2 inhibitor; or
• •They have clearly documented coronary artery disease (defined as a previous acute coronary syndrome, coronary stent or bypass surgery) or clearly documented heart failure (defined on the basis of a hospital admission, specialist diagnosis or an echocardiogram or other imaging modality); or
• •Pregnant or breast-feeding.