Breast cancer or acute leukemias, lymphomas (Hodgkin and non-Hodgkin) or sarcomas (osteo, soft tissue and Ewing) confirmed by histology and assigned for diseace-specific chemotheraphy
Confirmed menarche
ECOG performance status 0-1
Adequate bone marrow, renal, hepatic and cardiac functions and absence of other uncontrolled medical or psychiatric disorders
You may not be if
Demonstrated premature ovarian failure at time of randomization according to clinical or biochemical data
Previous or planned bilateral oophorectomy
Pregnancy or breastfeeding at time of start of chemotherapy
Other malignancy diagnosed within the last five years
Uncontrolled hypertension, heart, liver, kidney related or other uncontrolled medical or psychiatric disorders including previous or current diagnosis of anorexia
Known osteoporosis
Known low platelet count with increased bleeding risk or refractory thrombocytopenia in subjects with acute leukemias
Known or suspected allergy against triptorelin
Direct radiation of the gonads previous or planned (TBI allowed)
Mental inability, reluctance or language difficulties that result in difficulty understanding the meaning of study participation
