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Comparison of Programmed Intermittent Bolus Infusions of Spinae Plane Block Versus Paravertebral Block for Analgesia in Minimally Invasive Direct Coronary Artery Bypass Grafting
Paravertebral block (PVB) has been regarded as effective regimen for pain control after cardiac surgery. As a novel analgesia technique, erector spinae plane block (ESPB) has been reported to provide effective analgesia after thoracic and cardiac surgery. We hypothesized that the ESPB is non-inferior to PVB in treating pain in minimally invasive direct coronary artery bypass surgery.
Minimally invasive direct coronary artery bypass grafting has recently gained with popularity in treatment of coronary artery disease. Compared with conventional approach, it has advantages of less trauma and rapid recovery, but postoperative pain is severe, which may increase the risk of cardiopulmonary complications and cause chronic pain. Therefore, perioperative analgesia is crucial in minimally invasive direct coronary artery bypass grafting. Paravertebral block (PVB) has been regarded as effective regimen for pain control after cardiac surgery. As a novel analgesia technique, erector spinae plane block (ESPB) has been reported to provide effective analgesia after thoracic and cardiac surgery. We hypothesized that the ESPB is non-inferior to PVB in treating pain in minimally invasive direct coronary artery bypass surgery.
Age
18 - 75 years
Sex
ALL
Healthy Volunteers
No
Department of Anesthesiology,Peking University Third Hospital
Beijing, Beijing Municipality, China
Peking University Third Hosptial
Beijing, China
Start Date
March 1, 2022
Primary Completion Date
June 30, 2023
Completion Date
December 30, 2023
Last Updated
January 8, 2025
140
ACTUAL participants
Ropivacaine
DRUG
Lead Sponsor
Peking University Third Hospital
Collaborators
NCT05128890
NCT06409156
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT06528288