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Establishment of a Standard Operating Procedure for Screening of the Pathologies Associated With Prediabetes and Diabetes -The Wellness Transformation Network Pilot Study.
The purpose of the study is to establish a Standard Operating Procedure (SOP) for the screening of pathologies associated with prediabetes and type 2 diabetes.
The proposed study will enable screening of pathologies associated with cardiometabolic diseases (i.e., hypertension, prediabetes, insulin resistance, diabetes, and obesity). The Meal-Induced Insulinemia and Glycemia (MIG) score will correlate with those dysfunctions that are components of the Absence of Meal-Induced Insulinemia (AMIS) syndrome. Overall the study aims: 1. To establish an SOP for screening pathologies associated with cardiometabolic diseases using a combination of biometrics and metabolomics. 2. To compare a participant's MIG score and hepatalin levels following consumption of a standardized test meal containing macronutrients, and the measurement of several indices of organ health associated with diabetes (i.e., body composition, handgrip strength, spirometry, blood pressure, and heart rate variability). The study will involve 2 study visits: Visit 1 - Screening and Visit 2 - Intervention (Test meal administration and postprandial blood collection).
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
Yes
SNI Clinical Research
Winnipeg, Manitoba, Canada
Start Date
January 17, 2022
Primary Completion Date
April 5, 2022
Completion Date
April 5, 2022
Last Updated
April 22, 2022
15
ACTUAL participants
Standardized test meal
OTHER
Lead Sponsor
SciMar Ltd.
Collaborators
NCT07154186
NCT06933355
Data Source & Attribution
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