Long Covid After COVID-19 Infection With Omicron Variant

Objectives Primary objective: To investigate Long Covid symptoms after Omicron infection through monthly surveys for six months, compared to controls not infected. Secondary objective: To investigate acute symptoms during Omicron infection through the first survey shortly after the infection. Methods All confirmed COVID-19 patients in January 2022 will receive an invitation to participate in an online survey. We will send the online surveys in two separate bulks. The individuals with confirmed COVID-19 during the first half of January will receive the online survey first, at the same time as half of the controls. The rest of the COVID-19 cases will receive it during the first half of February, along with the rest of the control group. Outcomes Self-reported symptoms through the online survey compared to the symptoms in the control group. Hospitalization. Death. Statistical analyses We will report the results as numbers and percentages. We will stratify analyses by age groups, gender, and previous immunity through infection or vaccination. Population The target population is all infected Faroese COVID-19 patients during January 2022, when Omicron is expected to make up the majority of cases. Controls will be participants in two separate serological surveys with randomly selected individuals that have not had COVID-19 during December 2021 and January 2022 Variables for COVID-19 cases * Date of infection * Previous COVID-19 infection, date * Vaccination status and dates of vaccination * Self-reported symptoms during the acute phase of the infection, pre-made list by research group, rated as none, mild, moderate, and severe. * Option to write in other symptoms. * Weight and height * Self-reported severity of the disease course, rated as asymptomatic, mild, moderate, and severe. * Time to resolution of acute symptoms * Background information, including education level, current occupational status, smoking, co-morbidities, medicine use, and self-reported health. * Date of hospitalization, length of hospitalization, date of ICU, length of ICU, date of death. Variables for controls * Previous COVID-19 infection, date * Vaccination status and dates of vaccination * Self-reported symptoms during the last week, pre-made list by research group, rated as none, mild, moderate, and severe. * Option to write in other symptoms. * Weight and height * Self-reported severity of the disease course, rated as asymptomatic, mild, moderate, and severe. * Time to resolution of acute symptoms * Background information, including education level, current occupational status, smoking, co-morbidities, medicine use, and self-reported health. Publication The results will be published in international scientific journals and press releases on www.health.fo. Perspectives There is an urgent need to investigate Long Covid after an Omicron infection. This study can provide rapid answers to this question. Strengths of this planned study include the possibility of performing a nationwide survey and the rapid reporting of both long-term and short-term symptoms. Limitations include the possibility of a low participation rate.