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Determination of Vaginal Colonization and the Effect of an Oral Probiotic (PROSALVAG) | Clinical Trials | Clareo Health

COMPLETEDNA

Determination of Vaginal Colonization and the Effect of an Oral Probiotic (PROSALVAG)

Study to Determine Vaginal Colonization and Effect of an Oral Probiotic That Contains L.Rhamnosus, L. Plantarum and L. Crispatus in Women (PROSALVAG)

NCT05176535•Fertypharm

View on ClinicalTrials.gov

Summary

The aim of this study is to determine the efficacy of an oral nutraceutical with probiotics in restore vaginal health.

Detailed Description

After being informed about the study, all patients meeting the inclusion/exclusion criteria and giving written informed consent will receive a nutraceutical containing L. rhamnosus, L. plantarum and L. crispatus once daily.

Eligibility

Age

35 - 43 years

Sex

FEMALE

Healthy Volunteers

Yes

Inclusion Criteria

•Aged: 35-43 years old
•Vaginal pH \> 4,5 and low Lactobacillus count or Nugent score of 4-6
•With interest in getting pregnant and ideally in IVF waiting list
•History of recurrent genitourinary infections

Exclusion Criteria

•Any pathology that interferes with the study
•Current intake of food supplements or probiotics
•Current intake of contraceptives
•Use of oral or vaginal probiotics in the last 6 months
•Hypersensitivity to any of the components of the studied product
•Current vaginal infection
•Pregnant women
•Breastfeeding
•Use of intrauterine device
•Use of spermicide
+1 more criteria

Locations (1)

HM Fertility Centter Vallés

Alcalá de Henares, Madrid, Spain

Key Dates

Start Date

October 11, 2021

Primary Completion Date

January 15, 2024

Completion Date

May 28, 2024

Last Updated

December 4, 2025

Enrollment

ACTUAL participants

Conditions

Microbial ColonizationDysbiosisFertility Issues

Interventions

FertyBiotic Balance

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 4, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Determination of Vaginal Colonization and the Effect of an Oral Probiotic (PROSALVAG)

Inclusion Criteria

Exclusion Criteria

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