Role of Antihistaminic in Acute Renal Colic Prevent Pain Recurrence and Expulsion of Ureteric Stone ≤ 1cm

All the patients will be included within inclusion criteria After providing written informed consent, these patients were randomly divided into 2 groups by use of a computer-generated random number table. 1. history taken about patient pain onset, duration and type with scoring the pain by World Health Organization numerical pain score of 0-10. 2. Ultrasonography done to determine if kidney obstructed and grade of obstruction at the day 1 day 15 and day 30. 3. group A receive Tamsulosin 0.4mg in combination of NSAI drug if patient present with colic, if not in renal colic at bed time Tamsulosin 0.4mg with analgesic on demand, group B receive pheniramine maleate 50mg injection every 12hr for 24 hr in combination of Tamsulosin 0.4mg and NSAI drug then fexofenadine 180 mg in combination of Tamsulosin 0.4mg and NSAI drug on demand if patient present with colic. if not in renal colic at bed time fexofenadine 180 mg in combination of Tamsulosin with NSAI on demand. 4. In case of patient presented by acute renal colic the time of administration of treatment recorded and the time of relief pain recorded. 5. CT scan done to ensure urolithiases if no CT done at the first day and after 30 days. 6. Full labs done especially serum creatinine and serum uric acid.