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Camrelizumab Plus Chemoradiotherapy for Patients With Locoregional Cancer of Nasal Cavity and Paranasal Sinuses: a Phase II Multicenter Study
Patients with locoregional cancer of nasal cavity and paranasal sinuses are candidate for this study. All the eligible patients receive three cycles of induction chemotherapy (docetaxel 60mg/m2+cisplatin 60mg/m2+5-FU2.5g/m2,civ48h, q3w) followed by concurrent two cycles of cisplatin (80mg/m2,q3w) with curative intensity modulated radiotherapy. Besides, camrelizumab (200mg) is administrated every three weeks for a total of 11 cycles since the first day of induction chemotherapy. We aim to evaluate the three years failure free survival of these patients by the combination of camrelizumab with curative radiotherapy and chemotherapy.
Age
18 - 65 years
Sex
ALL
Healthy Volunteers
No
Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, China
Start Date
April 16, 2021
Primary Completion Date
April 16, 2024
Completion Date
April 16, 2024
Last Updated
November 10, 2021
57
ESTIMATED participants
camrelizumab
DRUG
Lead Sponsor
Sun Yat-sen University
NCT05512481
NCT05483374
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