Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Second Affiliated Hospital, Zhejiang University, School of Medicine
Age
18–40
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Meet the DSM-IV diagnostic criteria for schizophrenia, patients aged 18-40 years old have been treated with other antipsychotics for more than 8 weeks (inclusive) before being included, meet the diagnostic criteria for metabolic syndrome (IDF, 2005), and have not reached diabetes , Patients with diagnostic criteria for hypertension.
You may not be if
Female patients who are pregnant or breastfeeding;
Serious and unstable physical diseases, including: cardiovascular, respiratory, liver, kidney, gastrointestinal, nerve, endocrine, immune, blood system, narrow-angle glaucoma, history of seizures;
Patients with refractory schizophrenia;
Those who meet the DSM-IV standards for dementia or substance dependence (except tobacco);
Patients with a history of contraindications to ziprasidone or intolerance of ziprasidone;
Patients who use long-acting antipsychotic injections or oral medications;
Patients who have recently experienced prolonged QT interval, acute myocardial infarction, and decompensated heart failure;
Patients have recently taken drugs that can prolong the QT interval, such as dofetilide, sotalol, quinidine, other class Ia and III antiarrhythmic drugs, mesoridazine, thioridazine, Chlorpromazine, droperidol, pimozide, sparfloxacin, gatifloxacin, moxifloxacin, halofantrine, mefloquine, pentamidine, arsenic trioxide, levomethadone, dolastron methanesulfonate Acid, probucol or tacrolimus;
At the same time taking other drugs that can cause obesity, such as oral contraceptives;
Patients who have met metabolic syndrome before diagnosis and treatment of schizophrenia.
