Sleep Management And Recovery After Traumatic Brain Injury in Kids: Pilot Intervention of Melatonin

Inclusion Criteria

• •Inclusion:
• •Children age ≥6 years and \<19 years
• •Traumatic brain injury defined as disruption of the normal function of the brain resulting from blunt force injury with a severity defined as mild complicated, moderate, or severe by the Glasgow Coma Scale with the presence of intracranial injury on imaging
• •Admission to Oregon Health \& Science University Hospitals
• •Deemed likely to survive hospitalization by clinical care team
• •Able to tolerate enteral medications within 72 hours of admission
• •Child participant resides with parent or legal guardian
• •Exclusion:
• •Lack stable means of communication with study team (phone, email, mailing address)
• •Abusive trauma suspected or confirmed
• •Dialysis
• •Extracorporeal support (e.g. ECMO)
• •Significant liver injury defined as \>2x normal levels for AST or ALT
• •Clinical team safety concerns with use of intervention
• •Pregnancy
• •Prisoners