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Effectiveness of Compression Stocking on Overnight Fluid Shift in Obstructive Sleep Apnea Patients
Overnight rostral fluid shift is one of the contributing factors for worsening obstructive sleep apnoea (OSA). Fluid shift has been recognized to play a role in the pathophysiology of sleep apnoea. Previous studies shown that fluid from the leg redistributes to the neck at night increases the neck circumference, hence indicating fluid accumulation in the neck. OSA patients are more susceptible to developing upper airway narrowing in response to fluid shift from the leg to the head and neck region. Previous studies were mainly done on Caucasian patients. The pathophysiology of OSA in Caucasian patients and Asian patients are different but both suffer a similar degree of OSA. The investigators would like to investigate if reducing leg swelling by a simple non-invasive intervention of wearing compression stocking during the day can attenuate sleep apnoea, and whether compression stocking is generally acceptable and well-tolerated among the general OSA population in Asia.
Age
30 - 65 years
Sex
ALL
Healthy Volunteers
No
Khoo Teck Puat Hospital
Singapore, Singapore
Start Date
August 28, 2021
Primary Completion Date
November 12, 2022
Completion Date
December 27, 2022
Last Updated
April 10, 2023
29
ACTUAL participants
Compression stocking
DEVICE
Lead Sponsor
Khoo Teck Puat Hospital
NCT06430957
NCT07292922
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT07225686