A Study of SHR-A1904 in Patients With Advanced Solid Cancer

Exclusion Criteria

• •1. Plan to receive any other anti-tumor treatments during the study treatment period of this study
• •2. Received other clinical investigational products or treatments within 4 weeks before the first dose of the study
• •3. Received anti-tumor therapies such as chemotherapy, radiotherapy, biological therapy, targeted therapy, or immunotherapy within 4 weeks before the first dose of the study
• •4. Underwent a major surgery other than diagnosis or biopsy within 4 weeks before the first dose of the study
• •5. Subjects with known brain metastases
• •6. Grade II-IV cardiac insufficiency as per the New York Heart Association (NYHA) criteria; arrhythmia requiring long-term drug control; unstable angina or acute myocardial infarction within 6 months before the first dose of the study
• •7. presence of accompanying diseases (such as poorly controlled hypertension, serious diabetes mellitus, thyroid disorder, psychosis, etc.) that may pose serious risks to the safety of the subject or may affect the subject's ability to complete the study, or any other situation as judged by the investigator