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Pioneering Pre- and Post-Operative Integrative Care to Improve Thoracic Cancer Quality of Care - The Thoracic Peri-Operative Integrative Surgical Care Evaluation (POISE) Trial - Stage III
Despite enormous advances in thoracic surgery and oncology, two critical issues concern patients undergoing curative-intent surgery for lung, gastric and esophageal cancer: first, a majority (\~60%) of patients experience minor and major adverse events occurring during and in the days following surgery; second, patients worry about the significant risk of cancer recurrence and mortality months to years after surgery. These issues, combined with side effects of chemotherapy and radiation, have detrimental effects on health-related quality of life (HRQoL). On a deeper level, there is the problem of an ongoing failure to integrate and evaluate the best of what complementary medicine has to offer surgical oncology care. Too many clinical trials focus on single agent therapies, rather than broad multi-faceted individualized and integrative care interventions that are used in real world settings. The Thoracic POISE project has the overarching goal of improving care for thoracic cancer patients by impacting HRQoL, reducing surgical adverse events, prolonging overall survival and pioneering integrative care delivery.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
The Ottawa Hospital
Ottawa, Ontario, Canada
Michael Garron Hospital
Toronto, Ontario, Canada
Start Date
April 4, 2022
Primary Completion Date
December 1, 2028
Completion Date
December 1, 2029
Last Updated
January 30, 2026
20
ESTIMATED participants
Vitamin D3 Drops
DIETARY_SUPPLEMENT
Coriolus Versicolor
DIETARY_SUPPLEMENT
Trident SAP 66:33 Lemon
DIETARY_SUPPLEMENT
Probiotic Pro12
DIETARY_SUPPLEMENT
Provitalix Pure Whey Protein
DIETARY_SUPPLEMENT
Theracurmin 2X
DIETARY_SUPPLEMENT
Green Tea Extract
DIETARY_SUPPLEMENT
Nutrition Recommendations
OTHER
Physical Activity Recommendations
OTHER
Psychological Recommendations
BEHAVIORAL
Lead Sponsor
Ottawa Hospital Research Institute
Collaborators
NCT07485114
NCT07486219
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT06066138