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Molecular Profiling of Colorectal Cancer: A Translational Research Study With a Next Generation Sequencing Panel.
In this translational research study, Formalin-Fixed-Paraffin-Embedded (FFPE) tumor tissue blocks from patients with early-stage (II-III) colorectal cancer will be assessed for a comprehensive cancer gene panel from NIPD Genetics (https://www.nipd.com/) targeting regions in 37 clinically relevant cancer genes. The colorectal cancer panel includes an extended list of clinically relevant genes, designed to target clinically actionable and clinically significant mutations that will provide physicians with genetic information regarding a) prediction of the patient's response to targeted therapy, b) prognosis, that is, prediction of clinical outcome, c) diagnosis and molecular classification of colorectal cancer.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Hellenic Cooperative Oncology Group
Athens, Greece
Start Date
January 1, 2006
Primary Completion Date
September 1, 2021
Completion Date
September 1, 2022
Last Updated
April 28, 2021
300
ESTIMATED participants
Gene panel
DIAGNOSTIC_TEST
Lead Sponsor
Hellenic Cooperative Oncology Group
NCT06696768
NCT04704661
Data Source & Attribution
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