The Efficacy of Stabilized Chlorine Dioxide Rinse as a Chemical Adjuvant for Treatment of Per-implant Mucositis

Exclusion Criteria

• •Active Periodontitis or Peri-implantitis which requires definitive treatment.
• •Presence of oral local mechanical factors that could (in the opinion of the PI) influence the outcome of the study.
• •Presence of orthodontic appliances, or any removable appliances, that impinges on the tissues being assessed.
• •Presence of soft or hard tissue tumors of the oral cavity.
• •Patients treated with systemic antibiotic therapy or periodontal/mechanical/local delivery therapy within 12 weeks prior to study entry and throughout the study duration.
• •Patients chronically (i.e. two weeks or more) treated with non-steroidal anti-inflammatory drugs (NSAIDs) or any medications know to affect soft tissue condition (excluding treatment of Acetylsalicylic acid ≤ 100 mg/day).
• •Patients with uncontrolled diabetes, of any type, and/or patients with HbA1c test value \>7.5% dated 3 months prior to the screening visit.
• •Patients receiving radiation therapy to the head and neck area and/or receiving immunosuppressive therapy.
• •The presence of any medical or psychiatric condition or any other condition that, in the opinion of the Investigator, could affect the successful participation of the patient in the study.
• •Drug and alcohol abuse.
• •Patient participates in any other clinical study 30 days prior to the start of the study and throughout the study duration.
• •Subject is pregnant (based on pregnancy result) or lactating.
• •Subject is a smoker, or has been a smoker within the past 6 months.
• •Any other condition that may interfere with the study as judged by the PI