A Study to Evaluate the Efficacy and Safety of HR18042 Tablets in the Treatment of Postoperative Pain of Impacted Tooth.

Exclusion Criteria

• •1. any analgesic medication other than preoperative or intraoperative anaesthetic agents within 12h before taking trial medication medication
• •2. a longacting NSAID within 4 days,or a shortacting NSAID within 1 days prior to dosing.
• •3. any anti-depressive medication, selective serotonin reuptake inhibitors (SSRIs), diet pills et.al. with 30 days of study entry.
• •4. Oral surgical site combined with infection.
• •5. Severe cardiovascular and cerebrovascular diseases.
• •6. Severe gastrointestinal disease.
• •7. had a history of seizures or drug or alcohol abuse.
• •8. uncontrolled hypertension.
• •9. significant abnormal electrocardiogram
• •10. significant abnormal laboratory value.
• •11. Allergic to the study drug and ingredients.
• •12. Pregnancy, lactation or recent Pregnant plan;
• •13. Subjects who participated in a clinical research study involving an experimental drug before 30 days of study entry.
• •14. other conditions unsuitable for participation in the study.