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Long-term Recovery: Longitudinal Study of Neuro-behavioral Markers of Recovery and Precipitants of Relapse | Clinical Trials | Clareo Health

ACTIVE_NOT_RECRUITING

Long-term Recovery: Longitudinal Study of Neuro-behavioral Markers of Recovery and Precipitants of Relapse

NCT04788004•Virginia Polytechnic Institute and State University

View on ClinicalTrials.gov

Summary

The goals of this study are to provide a scientific understanding of recovery and relapse, as well as to identify novel targets for future relapse prevention interventions.

Detailed Description

The study will characterize long-term trajectories of recovery from alcohol use including the associated changes in psychosocial functioning and relapse status. By using an accelerated longitudinal design, competing neurobehavioral decision systems (CNDS) functioning (measured using delay discounting), psychosocial functioning, and relapse will be characterized over a 12-year period for individuals in alcohol use disorder (AUD) recovery.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. be ≥18 yrs old
•2. meet lifetime DSM-5 AUD criteria
•3. have a Recovery Initiation Date less than 10 years prior to the time of enrollment
•4. be able to read independently
•5. be free of legal problems that could limit participation
•6. reside in the U.S.
•7. anticipate continued Internet access (to ensure ongoing contact and data collection)
•8. be a registrant of the International Quit and Recovery Registry (IQRR)

Exclusion Criteria

•Minors will not be included
•Prisoners will not be included. If participants become incarcerated during this study, they will not be contacted to complete assessments during their incarceration. If the incarcerations ends during the study, they may be contacted to participate in assessments.
•Adults who are not capable of consenting on their own behalf

Locations (1)

Fralin Biomedical Research Institute at VTC

Roanoke, Virginia, United States

Key Dates

Start Date

September 8, 2022

Primary Completion Date

July 20, 2026

Completion Date

July 20, 2026

Last Updated

January 16, 2026

Enrollment

733

ACTUAL participants

Conditions

Alcohol Use Disorder

Interventions

Online survey

OTHER

Phenotyping Patients With Alcohol and Cannabis Use Disorders Using the Addictions Neuroclinical Assessment

NCT05855668

Alcohol Use DisorderCannabis Use Disorder

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RECRUITINGNA

Web-based Alcohol- or Cocaine-specific Inhibition Training in Adolescents and Young Adults With Substance Use Disorder

NCT07071779

Alcohol Use Disorder (AUD)Cocaine Use Disorder (CUD)+1 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 16, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Long-term Recovery: Longitudinal Study of Neuro-behavioral Markers of Recovery and Precipitants of Relapse

Inclusion Criteria

Exclusion Criteria

Phenotyping Patients With Alcohol and Cannabis Use Disorders Using the Addictions Neuroclinical Assessment

Web-based Alcohol- or Cocaine-specific Inhibition Training in Adolescents and Young Adults With Substance Use Disorder

Virtual Reality (VR) NATURE - Alcohol Use Disorder (AUD)

Anxiety During Abstinence in AUD

Effects of Tirzepatide on Alcohol Intake in Patients Diagnosed With Schizophrenia and Alcohol Use Disorder

Image-guided, Robot Navigated Transcranial Magnetic Stimulation (IR-TMS) for Alcohol Use Disorder (AUD)