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Evaluation of a LAMP Assay for T. Pallidum. Pertenue | Clinical Trials | Clareo Health

COMPLETED

Evaluation of a LAMP Assay for T. Pallidum. Pertenue

Clinical Evaluation of a Loop-mediated Isothermal Amplification Test for Treponema Pallidum Pertenue: A Diagnostic Tool to Support Yaws Eradication

NCT04753788•London School of Hygiene and Tropical Medicine

View on ClinicalTrials.gov

Summary

This is a diagnostic evaluation comparing the performance of real-time PCR performed at a national reference laboratory and a LAMP assay performed at a regional hospital for the diagnosis of yaws

Eligibility

Age

All ages

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Lesion consistent with yaws
•Positive treponemal and non-treponemal antibodies assessed by the DPP Syphilis Screen and Confirm RDT

Exclusion Criteria

•Unable to give consent

Locations (3)

Centre Pasteur

Yaoundé, Cameroon

Institut Pasteur

Abidjan, Côte d’Ivoire

Noguchi Memorial Institute of Medical Research

Accra, Ghana

Key Dates

Start Date

March 15, 2021

Primary Completion Date

September 23, 2023

Completion Date

September 30, 2024

Last Updated

March 24, 2025

Enrollment

563

ACTUAL participants

Conditions

Yaws

Interventions

PCR

DIAGNOSTIC_TEST

LAMP

DIAGNOSTIC_TEST

Repurposing Clinically Approved Drugs for Yaws with an Insight Into the Cutaneous Ulcer Disease Syndrome (Trep-AByaws)

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YawsCutaneous Ulcer

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COMPLETEDPHASE4

Evaluation of an Intensive 3-round MDA Strategy Towards Yaws Eradication

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Yaws

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COMPLETEDPHASE3

Safety of Co-administration of IDA and Azithromycin for NTDs ( ComboNTDs )

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 24, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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