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UNKNOWNNA

NHF vs. COT in Hypoxemic Pandemic Viral Illness

Clinical Effects of Nasal High-flow Compared to Oxygen in Acute Viral Illness

NCT04750408•Jens Bräunlich

Summary

The study compares oxygen and NHF in patients with acute viral illness. The duration will be 72h. After them physiological parameters and the outcome will be evaluated.

Eligibility

Age

18 - 100 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•acute hyperemic viral illness
•acute hyperemic or hypercapnia respiratory failure

Exclusion Criteria

•intubation criteria
•indication for NIV therapy
•influences of primary endpoint (rip fracture, lung embolism)
•tracheostomy
•other interventional trials
•noncompliance

Locations (1)

Klinikum Emden

Emden, Germany

Key Dates

Start Date

January 22, 2021

Primary Completion Date

June 22, 2022

Completion Date

June 22, 2022

Last Updated

March 31, 2022

Enrollment

ESTIMATED participants

Conditions

Acute Viral BronchitisHypoxemic Respiratory FailureHypercapnic Respiratory Failure

Interventions

Standard oxygen

DEVICE

Nasal high-flow

DEVICE

Contacts

Jens Bräunlich, MD

CONTACT

+494921981598 highflow@web.de

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RECRUITINGNA

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 31, 2022Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

NHF vs. COT in Hypoxemic Pandemic Viral Illness

Inclusion Criteria

Exclusion Criteria

Helmet NIV vs. CPAP vs. High-flow Nasal Oxygen in Hypoxemic Respiratory Failure

High Flow Nasal Cannula Versus Non-Invasive Ventilation in Exacerbations of Chronic Obstructive Pulmonary Disease

Pilot Physiological Evaluation of an Investigational Mask with Expiratory Washout.

ROX Index for the Timing of Intubation in Nasal High Flow

Protocolized Weaning of High-Flow Nasal Cannula in Adult Patients

Efficacy of Volume Ventilation in Patients With Acute Respiratory Failure at Risk of Obstructive Apneas or Obesity Hypoventilation