Cohorte Nationale VIH-2

The HIV2 study is an open cohort of prospective, multicentric, national observation. The main objective is to study HIV-2 infection in adult patients followed in France.

The secondary objectives are : * Describe the epidemiological and clinical characteristics of participants infected with HIV-2, and the immuno-virological characteristics of the infection. * To study the clinical and immunological progression of HIV-2 infection and the prognostic factors of this evolution. * Study the response to antiretroviral treatment (clinical, immuno-virological) and contribute to the identification of the antiretroviral strategies and combinations most suited to the particularities of the infection. * Allow an evaluation of the care practices of participants followed in French hospitals * Provide a bank of clinical-biological data and samples allowing the performance of virological and / or immunological studies on HIV-2 infection. The follow-up of the participants is different according to the therapeutic status of the participants, naive of antiretroviral treatment or already treated with antiretrovirals.