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A Study to Compare the Effectiveness of Different High-intensity Interval Training Programs in Cardiac Rehabilitation | Clinical Trials | Clareo Health

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A Study to Compare the Effectiveness of Different High-intensity Interval Training Programs in Cardiac Rehabilitation

Efficacy of Prescription Methods for High-intensity Interval Training in Patients Enrolled in Outpatient Cardiac Rehabilitation

NCT04555512•Mayo Clinic

View on ClinicalTrials.gov

Summary

The purpose of the study is to examine the effect of two different high intensity interval training (HIIT) prescription approaches on improving fitness, heart function, and the ability of the body's muscles to receive oxygen.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Adult 18 years and older.
•English speaking.
•Able to provide consent.
•Has a qualifying indication for center-based cardiac rehabilitation that is non-surgical (i.e., Acute coronary syndrome, myocardial infarction, percutaneous coronary intervention, and stable angina).

Exclusion Criteria

•Participants referred to cardiac rehabilitation following coronary artery bypass surgery, heart valve repair/replacement, heart transplant, or those with ventricular assist devices.
•Patients unable/unwilling to provide informed consent will not be enrolled.
•Patients identified as having a contraindication to high intensity exercise.

Locations (1)

Mayo Clinic in Rochester

Rochester, Minnesota, United States

Key Dates

Start Date

June 23, 2021

Primary Completion Date

December 31, 2025

Completion Date

December 31, 2026

Last Updated

January 14, 2026

Enrollment

ESTIMATED participants

Conditions

Cardiac Rehabilitation

Interventions

Progressive High Intensity Interval Training (PRO-HIIT)

OTHER

Constant High Intensity Interval Training (CON-HIIT)

OTHER

OPTImizing CArdiac REhabilitation by REfining Sleep and STress

NCT06505109

Cardiovascular DiseasesCardiac Rehabilitation

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RECRUITING

The Italian Alliance for Cardiovascular Rehabilitation and Prevention (ITACARE-P) Registry: An Observational Study on Cardiac Rehabilitation in Patients With Coronary Disease or Heart Failure

NCT07094737

Cardiac RehabHeart Failure+5 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 14, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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A Study to Compare the Effectiveness of Different High-intensity Interval Training Programs in Cardiac Rehabilitation

Inclusion Criteria

Exclusion Criteria

OPTImizing CArdiac REhabilitation by REfining Sleep and STress

The Italian Alliance for Cardiovascular Rehabilitation and Prevention (ITACARE-P) Registry: An Observational Study on Cardiac Rehabilitation in Patients With Coronary Disease or Heart Failure

Integration of Telemedicine and Home-Based Cardiac Rehabilitation: Feasibility, Efficacy, and Adherence

Patient-centered Personalized Cardiac Rehabilitation in Post Acute Coronary Syndrome (BREAK-trial)

Electronic Cardiac Rehabilitation (eCardiacRehab) Feasibility Study

Exercise Prescription in Cardiac Rehabilitation Mediated by Autonomic Function