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Platelet-Rich Plasma (PRP) for Treatment of Symptomatic Lumbar Facet Syndrome of the Spine | Clinical Trials | Clareo Health

COMPLETEDEARLY_PHASE1

Platelet-Rich Plasma (PRP) for Treatment of Symptomatic Lumbar Facet Syndrome of the Spine

A Pilot Trial Evaluating the Feasibility of Using Platelet-Rich Plasma (PRP) for Treatment of Symptomatic Osteoarthritis of the Lumbar Facet Joint(s) of the Spine

NCT04522674•University of Colorado, Denver

View on ClinicalTrials.gov

Summary

The purpose of this study is to investigate the feasibility of standardized autologous platelet rich plasma injections into osteoarthritic lumbar facet joints to treat back pain and improve patient function.

Eligibility

Age

18 - 95 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Suspicion of z-joint mediated low back pain
•Pain rating of ≥4/10 on a VAS scale
•Symptom duration of 3 or more months
•Failed conservative therapy (minimum of PT and pain medications)
•Have diagnosis of lumbar facet syndrome after MRI, X-ray, or CT imaging of any severity and a medial branch block with local anesthetic that confirms lumbar facet pathology.

Exclusion Criteria

•Inability to undergo fluoroscopically guided procedures
•Current pregnancy
•Prior spinal surgery with hardware
•Intolerance to local anesthesia, contrast medium, or blood derivatives
•Local or systemic infection or spinal infection
•Irreversible coagulopathy
•Patients that require strict anticoagulation and cannot be off antiplatelet medication for at least a week
•Less than 18 years of age
•Corticosteroid shot within last 3 months into affected lumbar facet joint because of concern of damage to cartilage in the joint in that time period.
•Patients with workman compensation related back pain
+2 more criteria

Locations (1)

University of Colorado School of Medicine Spine Center

Aurora, Colorado, United States

Key Dates

Start Date

February 19, 2021

Primary Completion Date

April 28, 2022

Completion Date

April 28, 2022

Last Updated

May 4, 2022

Enrollment

ACTUAL participants

Conditions

Platelet-Rich Plasma

Interventions

Autologous platelet rich plasma

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 4, 2022Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Platelet-Rich Plasma (PRP) for Treatment of Symptomatic Lumbar Facet Syndrome of the Spine

Inclusion Criteria

Exclusion Criteria

The Efficacy and Safety of Pulsed Radiofrequency Combined With Platelet-rich Plasma for Infraorbital Neuralgia

The Effectiveness of the Combination of PRP and ESWT in Lateral Epicondylitis

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