About Pricing FAQs Providers Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

Back to clinical trial search

COMPLETEDNANCT04430465

Effects of Wholegrains on Children's Health (KORN)

KORN investigates the effects of wholegrain oat and rye intake on health and cognitive wellbeing in children with overweight.

Lead sponsor: University of Copenhagen•1 locations•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Sponsors

Lead Sponsor

University of Copenhagen

Collaborators

Chalmers University of Technology

The purpose of KORN is to investigate the effects of wholegrain oat and rye intake on cardiometabolic health in slightly overweight 8-13-year-old children. Moreover, KORN aims to investigate effects on body weight and body composition, inflammatory markers, gastrointestinal wellbeing and cognitive function and explore the potential underlying mechanisms through assessment of changes in the children's gut microbiota as well as potential genotype-dependent and sex-specific effects. The study has a randomized controlled cross-over design. In two 8-week dietary periods the children will receive grain products (cereals, breads, pasta etc) with either high or low content of wholegrain from oat and rye in random order. Measurements and biological sampling will be performed at 0, 8 and 16 weeks.

Age

8 - 13 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Boys and girls 8-13 years of age
•Be overweight i.e. have a parent-reported BMI of at least +1 standard deviation above the median according to the age and sex-standardized Danish growth curves
•Be healthy
•Like grain products and eat them daily
•Speak Danish in order to understand the study procedures
•At least one parent must read and speak Danish, in order to be properly informed about the study procedures
•Parents must have freezer capacity for 2 weeks bread provision

Exclusion Criteria

•Allergy or intolerance to the study foods, including gluten
•Use of dietary fiber supplements (e.g. HUSK) or probiotic supplements
•Dieting or on a special diet
•Serious chronic illnesses and diseases that may interfere with study outcomes
•Use of medication that may affect study outcomes, including use of antibiotics the last month
•Concomitant participation in other studies involving dietary supplements, drugs or blood sampling
•Living in a household with another participating child

Related studies

RECRUITINGPhase 2

Equol and Vascular Function in Women With Chronic Kidney Disease

NCT07194590 · Chronic Kidney Disease (Stage 3-4), Vascular Function, and more

Effect of Hot Spring Therapy on Cognitive Function Recovery During Altitude Training

NCT07608913 · Altitude Training Adaptation, Cognitive Function, and more

This Study Investigates β-hydroxy-β-methylbutyrate (HMB) and 2-hydroxybenzylamine (2-HOBA), When Administered Either Individually or in Combination Contributes to an Increased Quality of Health, Specifically Improving Muscular Strength and Cognitive Functioning in Adults Over the Age of 65.

NCT07419633 · Muscle, Cognitive Functioning, and more

RECRUITINGPhase 2

Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)

NCT06636786 · Acute Stress Reaction, Acute Stress Disorder, and more

Brain Stimulation Effects on Cognitive Task Performance

NCT05556655 · Cognitive Function

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 7, 2021Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment55

Start dateSep 2020

Last updatedMay 7, 2021

Condition

Cardiometabolic Health Gastro-intestinal Wellbeing Cognitive Function Overweight

Locations shown

Department of Nutrition, Exercise and Sports, University of Copenhagen

Frederiksberg

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 7, 2021Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions