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Evaluation of Patients After Cardiac Surgery: Novel Ultrasound Parameters for Quantification of Renal Perfusion & Analysis of Phenylephrines' Effect on Invasive Haemodynamics and Echocardiographic Measures | Clinical Trials | Clareo Health

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Evaluation of Patients After Cardiac Surgery: Novel Ultrasound Parameters for Quantification of Renal Perfusion & Analysis of Phenylephrines' Effect on Invasive Haemodynamics and Echocardiographic Measures

NCT04419662•Aarhus University Hospital

View on ClinicalTrials.gov

Summary

To investigate the influence of PEEP (Positive end-expiratory pressure), changes in preload (patient position) and changes in afterload (phenylephrine) on ultrasound measures of renal perfusion in patients after uncomplicated cardiac surgery. To investigate the effects of phenylephrine on both invasive measures of the systemic- and pulmonary circulation and, secondarily, to assess the induced changes in echocardiographic indices of left- and right ventricular systolic- and diastolic function.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•All patients ≥ 18 years scheduled for open elective cardiac surgery at the Department of Cardiothoracic \& Vascular Surgery, Aarhus University Hospital.

Exclusion Criteria

•Insufficient ultrasonographic imaging of the kidneys
•Known morphological kidney disease
•Preoperative dialysis
•Chronic atrial fibrillation
•Planned mitral valve surgery

Locations (1)

Aarhus University Hospital, Department of Anaesthesiology

Aarhus, Denmark

Key Dates

Start Date

May 25, 2020

Primary Completion Date

May 30, 2021

Completion Date

May 31, 2021

Last Updated

August 6, 2021

Enrollment

ACTUAL participants

Conditions

Ultrasonography, RenalCardiac SurgeryHemodynamicsPhenylephrineRenal PerfusionEchocardiographyAnesthesia

Interventions

Phenylephrine

DRUG

Combination of PEEP and positioning

OTHER

Diagnosis of Postoperative Atrial Fibrillation by a Smartwatch

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Atrial FibrillationCardiac Surgery

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RECRUITING

Prognostic Value of Novel Biomarkers on Adverse Renal Outcomes in High-Risk Cardiac Surgery Patients

NCT07418242

Cardiac Surgery Associated - Acute Kidney InjuryCritical Illness

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 6, 2021Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Evaluation of Patients After Cardiac Surgery: Novel Ultrasound Parameters for Quantification of Renal Perfusion & Analysis of Phenylephrines' Effect on Invasive Haemodynamics and Echocardiographic Measures

Inclusion Criteria

Exclusion Criteria

Diagnosis of Postoperative Atrial Fibrillation by a Smartwatch

Prognostic Value of Novel Biomarkers on Adverse Renal Outcomes in High-Risk Cardiac Surgery Patients

Colchicine's Effect on Inflammatory Markers

Submaximal Cardiopulmonary Exercise Testing for Detection of Myocardial Injury After Noncardiac Surgery

Difficult Airway Incidence in Cardiovascular Surgery and a Prediction Model Development

LSALT Peptide for Prevention or Attenuation of Acute Kidney Injury (AKI) in Patients Undergoing On-Pump Cardiac Surgery