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Monitoring Noninvasively for Infusion and Transfusion Optimization | Clinical Trials | Clareo Health

WITHDRAWNNA

Monitoring Noninvasively for Infusion and Transfusion Optimization

Monitoring Noninvasively for Infusion and Transfusion Optimization in a Randomized (MONITOR) Trial

NCT04388722•Masimo Corporation

Summary

This is a multicenter, cluster randomized controlled trial to assess the effects of an optimized intraoperative fluid and blood management strategy on postoperative complications.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•18 years or older at the time of consent.
•Ability to provide written informed consent.
•Scheduled for non-urgent major surgery with general anesthesia
•At least one finger available and accessible for performing non-invasive pleth variability index (PVi) and hemoglobin (SpHb) monitoring.
•The Attending surgeon, attending anesthesiologist and the clinical care team agree with enrollment in the study, including the restrictions on monitoring procedures defined in the control group.

Exclusion Criteria

•Untreated or uncontrolled hypertension defined as mean arterial pressure (MAP) greater than 120 mmHg, despite medications.
•Chronic kidney disease with glomerular filtration rate \<30 ml/min/1.73 m2 or requiring renal-replacement therapy for end-stage renal disease.
•Surgeries where no bleeding is expected to occur (i.e., total knee surgery where blood loss is prevented by use of tourniquet).
•Surgeries performed in the prone position.
•Acute cardiovascular event, including acute or decompensated heart failure and acute coronary syndrome.
•Aortic pathology that could lead to misinterpretation of hemodynamic variables (e.g. intra- aortic balloon pump, thoracic aorta aneurysm).
•Renal vascular surgery.
•Preoperative sepsis.
•Circulatory shock.
•Preoperative vasoactive substance infusion before study entry.
+9 more criteria

Key Dates

Start Date

June 1, 2020

Primary Completion Date

December 1, 2020

Completion Date

December 1, 2020

Last Updated

July 23, 2021

Conditions

Post Operative HemorrhageTransfusion Related ComplicationBlood Transfusion Associated Adverse ReactionsHypovolemia

Interventions

Pulse CO-Oximeter Sensor

DEVICE

Transfusion Surveillance in Anaesthesia

NCT06403163

Transfusion ReactionTransfusion Related Complication+6 more

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RECRUITINGNA

Respiratory Trends During Blood Transfusions in Newborns.

NCT06443515

Blood Transfusion ComplicationBlood Transfusion Associated Adverse Reactions+2 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 23, 2021Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Monitoring Noninvasively for Infusion and Transfusion Optimization

Inclusion Criteria

Exclusion Criteria

Transfusion Surveillance in Anaesthesia

Respiratory Trends During Blood Transfusions in Newborns.

Impact of Transfusional Practice on the Morbidity and Mortality of Patients in Intensive Care Unit

Evaluation of the Quantra QStat System in Obstetric Patients

Individualized or Conventional Transfusion Strategies During Peripheral VA-ECMO

Patient Blood Management for Massive Obstetric Hemorrhage