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A Retrospective Cohort Study Outcome of Treatment in Asymptomatic Stage 4 Colorectal Cancer : Primary Tumor Resection vs. No Primary Tumor Resection
In asymptomatic Stage 4 colorectal cancer, the treatment varies between many hospitals and countries. Some studies found that primary tumor resection had better survival rates and a lower risk of mortality. But many studies found significant benefits in survival in sub groups of the population such as age less than 70 years, WHO performance status \<2, no extra-hepatic metastasis, liver tumor burden \<50%. However some studies showed no survival benefits in primary tumor resection. So this study will focus on survival, adverse events, complications in primary tumor resection and no primary tumor resection in asymptomatic Stage 4 colorectal cancer.
The retrospective study of patients in asymptomatic Stage 4 colorectal cancer received treatment at Ramathibodi Hospital and excluded symptomatic primary tumors such as obstruction, perforation that required surgery, carcinomatosis peritoneii, and patients with secondary cancer diagnosis in the past 5 years.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Chairat Supsamutchai
Bangkok, Bankok, Thailand
Start Date
January 1, 2017
Primary Completion Date
March 1, 2020
Completion Date
March 31, 2020
Last Updated
April 6, 2020
135
ACTUAL participants
primary tumor resection group
PROCEDURE
Lead Sponsor
Mahidol University
NCT04704661
NCT05038254
Data Source & Attribution
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