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A Study to Evaluate TRS01 Eye Drops in Participants With Active Non-infectious Anterior Uveitis | Clinical Trials | Clareo Health

COMPLETEDPHASE1/PHASE2

A Study to Evaluate TRS01 Eye Drops in Participants With Active Non-infectious Anterior Uveitis

A Randomized, Double-Masked, Dose-Ranging Study to Evaluate the Safety and Tolerability of TRS01 Eye Drops in Participants With Active Non-infectious Anterior Uveitis.

NCT04222712•Tarsier Pharma

View on ClinicalTrials.gov

Summary

The objective of this study is to evaluate the safety of TRS01 eye drops in participants with active non-infectious anterior uveitis .

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•18 years of age or older
•Able to provide informed consent, follow instructions and complete all required study visits for the duration of the study.
•Diagnosed with active non-infectious anterior uveitis requiring an increase or initiation of topical steroids for management of ocular inflammation.
•An eligible subject must have:
•Non-infectious active anterior uveitis with anterior chamber cells Grade 2 or Grade 3, as specified per protocol.
•Must have vision ≥ 20/40 in the non-study eye.
•Use adequate birth control by men and women, if of reproductive potential and sexually active, as specified per protocol.

Exclusion Criteria

•Any form of infectious uveitis
•Active retinitis
•Cancer or melanoma that is actively treated with immunotherapy
•Pregnancy / lactation
•Receiving specific medication/interventions as specified per protocol

Locations (2)

Palisades Park

Palisades Park, New Jersey, United States

San Antonio

San Antonio, Texas, United States

Key Dates

Start Date

February 1, 2020

Primary Completion Date

August 24, 2020

Completion Date

August 24, 2020

Last Updated

October 5, 2023

Enrollment

ACTUAL participants

Conditions

Non-infectious Anterior Uveitis

Interventions

TRS01 eye drops

DRUG

TRS01 eye drops

DRUG

Tacrolimus Ophthalmic Solution for the Treatment of Non-infectious Anterior Uveitis

NCT07285070

Non-infectious Anterior Uveitis

View study

COMPLETEDPHASE3

A Study of TRS01 in Subjects With Active Non-infectious Anterior Uveitis Including Subjects With Uveitic Glaucoma

NCT05042609

Non-infectious Anterior UveitisUveitic Glaucoma

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 5, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

A Study to Evaluate TRS01 Eye Drops in Participants With Active Non-infectious Anterior Uveitis

Inclusion Criteria

Exclusion Criteria

Tacrolimus Ophthalmic Solution for the Treatment of Non-infectious Anterior Uveitis

A Study of TRS01 in Subjects With Active Non-infectious Anterior Uveitis Including Subjects With Uveitic Glaucoma

Safety and Efficacy Study of DSP-Visulex for the Treatment of Anterior Uveitis