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A Pilot Feasibility Study of Activated Charcoal in Healthy Volunteers | Clinical Trials | Clareo Health

COMPLETEDEARLY_PHASE1

A Pilot Feasibility Study of Activated Charcoal in Healthy Volunteers

A Pilot Feasibility Study of Activated Charcoal in Healthy Adult Volunteers

NCT04204772•Masonic Cancer Center, University of Minnesota

Summary

This is a pilot study designed to test feasibility, tolerability, and safety of medical grade oral Activated Charcoal (AC) in 12 healthy volunteers. To determine the two most palatable and tolerable AC combinations. There will be a total of 4 combinations (2 AC doses and 2 solutions) in stage 1. Each participant will drink an assigned combination every day for 3 consecutive days (Monday, Tuesday, Wednesday, "M/T/W") and switch to a different assigned combination M/T/W the following week. AC solution assignments will be defined before the study using a balanced incomplete block design. Each subject will rate their experience using a 5-point scale every day for the 12 days they are on study.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Age ≥18 years
•No use of prescription medications, including oral birth control, currently or in the last 30 days
•Sexually active women must be using an effective form of contraception. Note that subjects who are on oral contraception should use an additional form of contraception such as barrier methods, as AC may interfere with the efficacy of oral contraceptive
•Voluntary written consent signed before performance of any study-related procedure

Exclusion Criteria

•At risk of GI hemorrhage or perforation due to underlying pathology, recent surgery, or medical conditions that could be adversely affected by the administration of AC
•Planning to have an endoscopic procedure
•Known hypersensitivity to AC
•Non-English speakers

Locations (1)

Masonic Cancer Center at University of Minnesota

Minneapolis, Minnesota, United States

Key Dates

Start Date

January 22, 2020

Primary Completion Date

March 31, 2021

Completion Date

March 31, 2021

Last Updated

October 26, 2023

Enrollment

ACTUAL participants

Conditions

Healthy Adult Volunteers

Interventions

Activated charcoal and Tap Water

BIOLOGICAL

Activated Charcoal and Apple Juice

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 26, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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