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Visuocortical Dynamics of Affect-Biased Attention in the Development of Adolescent Depression
Rates of depression increase rapidly during adolescence, especially for girls, and, thus, research is needed to spur the development of novel interventions to prevent adolescent depression. This project seeks to determine if a novel visuocortical probe of affect-biased attention (i.e., steady-state visual evoked potentials derived from EEG) can 1) be used to prospectively predict depression using a multi-wave repeated measures design and 2) modify affect-biased attention and buffer subsequent mood reactivity using real time neurofeedback. This work could ultimately lead to improved identification of adolescents who are at high risk for depression and directly inform the development of mechanistic treatment targets to be used in personalized intervention prescriptions for high-risk youth.
Age
13 - 15 years
Sex
FEMALE
Healthy Volunteers
Yes
Western Psychiatric Institute and Clinic
Pittsburgh, Pennsylvania, United States
Start Date
October 16, 2019
Primary Completion Date
September 23, 2024
Completion Date
March 30, 2025
Last Updated
November 13, 2025
15
ACTUAL participants
Neurofeedback
OTHER
Lead Sponsor
University of Pittsburgh
Collaborators
NCT07360600
NCT06793397
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