KRN125 for Mobilization of Hematopoietic Stem Cells

Exclusion Criteria

• •Subjects with a current medical history or who have been judged to be inappropriate for the study (e.g., significant neurological, hepatic, renal, endocrine, cardiovascular, blood, gastrointestinal, respiratory, and metabolic diseases, malignancies, myeloproliferative disorder, or psychiatric disorders)
• •Individuals with alcohol or drug dependence, or individuals who have not tested negative for all drugs of abuse in the preliminary test
• •Subjects with a history or current history of drug allergy or symptomatic allergy
• •.Active infection or history of recurrent infection- However, only patients who are HBsantibody-positive by hepatitis B vaccination and whose HBV-DNA is less than the lower limit of quantitation will be allowed to participate in this study.
• •Subjects who used drugs within 2 weeks before administration of the investigational drug.
• •Subjects who have had at least 200 mL of blood drawn within 3 months before administration of the investigational drug.
• •Pregnant or lactating