Broken or inflamed skin at the second intercostal space parasternal chest wall areas
Psychological or social factors that would impair compliance with the study protocol
Any major non-COPD chronic co-morbidity that may contribute significantly to risk of readmission, including (but not limited to) severe heart failure (left ventricular ejection fraction \<30%), malignancy (active treatment or palliation), end stage renal failure and significant neuromuscular disease
Planned travel away from home in the 30-day post-discharge period
Clareo Health | The Role of HNHF to Improve Clinical Outcomes Following Severe AECOPD