Anti-inflammatory Effects of Topical Erythromycin and Clindamycin in Acne Patients

Exclusion Criteria

• •1. Severe acne where systemic treatment is needed
• •2. Use of any topical (anti-acne) medication (prescription or OTC) within 2 weeks prior to baseline
• •3. Use of any oral/systemic treatment for acne, including oral antibiotics, excluding OAC, within 4 weeks prior to baseline
• •4. Use of systemic isotretinoin within 6 months prior to baseline
• •5. History of pathological scar formation (keloid, hypertrophic scar)
• •6. Known hypersensitivity to erythromycin or clindamycin, drugs of the same class, or any of their excipients.
• •7. Known contact dermatitis reaction to any product
• •8. Tanning due to sunbathing, excessive sun exposure or a tanning booth within 3 weeks of enrollment.
• •9. Participation in an investigational drug or device study within 3 months prior to screening or more than 4 times a year.
• •10. Loss or donation of blood over 500 mL within three months (males) or four months (females) prior to screening
• •11. Pregnant, a positive pregnancy test, intending to become pregnant, or breastfeeding