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Titanium Zirconium (TiZr) Mini Implants | Clinical Trials | Clareo Health

ACTIVE_NOT_RECRUITINGNA

Titanium Zirconium (TiZr) Mini Implants

Is the Stabilization of a Mandibular Overdenture Employing Four Novel One-piece Immediately Loaded TiZr Implants With Miniaturized Stud-type Attachments a Feasible Alternative to Two Two-piece Early Loaded Tissue-level Implants With Regular Stud-type Attachments?

NCT03837158•University of Bern

View on ClinicalTrials.gov

Summary

H0: "Within the first year post-placement, four interforaminally placed, immediately loaded 2.4 mm narrow-diameter one-piece TiZr implants with miniaturized stud-type attachments show improved patient-reported outcome measures (PROMS) compared to two interforaminally placed, early loaded, TiZr two-piece implants with stud-type attachments to retain a mandibular overdenture."The specific aim is to compare both treatment alternatives to evaluate which one may be recommended for elderly edentulous patients.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•At patient level:
•* Written informed consent
•* Age ≥ 18 years
•* Sufficient complete dentures (Marxkors and Ferger, 1989) not older than 1 year
•* Patient is unsatisfied with mandibular denture to the degree that he/she seeks treatment
•At site level:
•* Healed edentulous mandible (minimum 8 weeks since last extraction)
•* Minimal ridge dimensions 5.5 mm (width) by 12 mm (height) in the anterior (interforaminal) area, allowing the placement of 3.3 (endosseous diameter) by 10 mm (length) implants
•* Opposing dentition: complete denture on a edentulous maxilla
•* Physical status (PS) 1 and 2 (American Society of Anesthesiologists)

Exclusion Criteria

•At patient level
•* Any physical or mental disorder that would interfere with the ability to perform adequate oral hygiene or the capability of providing written informed consent and compliance to the protocol
•* Any disorder that would interfere with wound healing or represent a contraindication for oral surgery such as, but not limited to, uncontrolled diabetes or conditions resulting in or requiring immunosuppression, radiation, chemotherapy, frequent use of antibiotics or antiresorptive medication such as bisphosphonates
•* Pregnancy or lactation
•* Heavy smoking habit with \> 20 cig/d
•* Severe bruxism or clenching habits, present oro-facial pain
•At site level:
•* Ridge defects requiring staged bone augmentation procedures (simultaneous Guided Bone Regeneration (GBR) within the ridge contour allowed)

Locations (2)

Private Practice Dr. B. Wallkamm

Langenthal, Canton of Bern, Switzerland

University of Bern

Bern, Switzerland

Key Dates

Start Date

September 1, 2019

Primary Completion Date

September 10, 2024

Completion Date

August 1, 2033

Last Updated

February 18, 2026

Enrollment

ACTUAL participants

Conditions

Dental Implants

Interventions

early loading

PROCEDURE

immediate loading

PROCEDURE

Clinical and Radiographic Evaluation of Dentsply Sirona PrimeTaper Implants

NCT05500755

Dental Implants

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RECRUITINGNA

Clinical Evaluation of a Modified Technique for Free Gingival Graft Stabilization Using Titanium Fixation Tacs Around Implants Versus Conventional Suturing Technique

NCT07019428

Free Gingival GraftSoft Tissue Augmentation Around Dental Implants+1 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 18, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Titanium Zirconium (TiZr) Mini Implants

Inclusion Criteria

Exclusion Criteria

Clinical and Radiographic Evaluation of Dentsply Sirona PrimeTaper Implants

Clinical Evaluation of a Modified Technique for Free Gingival Graft Stabilization Using Titanium Fixation Tacs Around Implants Versus Conventional Suturing Technique

The Application of Root Analogy Implant in Immediate Implantation

Implant-related Outcomes in the Context of Maxillary Sinus Lifting

Clinical Evaluation of a Hyperbolic Paraboloid Triple-Abutment on Morse Taper Dental Implants

Anterior Mandibular Region for Immediate Implant Placement