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Evaluation of Soybean Peptides Product on Regulation of Blood Pressure Effect by Clinical Trial
This is the report to assess supplementation with soybean peptides on blood pressure among people with mild hypertension. Overall, soybean peptide consumption for 8 weeks could successfully reduce mean diastolic and systolic BP through the suppression of Angiotensin-converting enzyme (ACE) linked to downstream suppression of angiotensin II formation, which further decreases the sympathetic outflow that leads to hypertension.
This is the report to assess supplementation with soybean peptides on blood pressure among people with mild hypertension. Thirty subjects with systolic blood pressure (SBP) between 120 and 159 mm Hg and/or diastolic blood pressure (DBP) between 80 and 99 mm Hg were randomized to ingest 2 bags of soybean peptides or placebo per day for 8 weeks of a stage. Anthropometric measurements (blood pressure, body weight, body fat) and blood biochemical markers including fasting blood glucose (FBG), albumin, total cholesterol (TC), triglyceride (TG), HDL-C, LDL-C, creatinine (Cr), blood urea nitrogen (BUN), AST, ALT) were examined every four weeks.
Age
20 - 80 years
Sex
ALL
Healthy Volunteers
Yes
Chung Shan Medical University
Taichung, Taiwan
Start Date
March 1, 2016
Primary Completion Date
October 1, 2016
Completion Date
January 1, 2017
Last Updated
May 24, 2021
30
ACTUAL participants
Soybean peptides
DIETARY_SUPPLEMENT
Placebo
DIETARY_SUPPLEMENT
Lead Sponsor
Chung Shan Medical University
NCT02417740
NCT07073820
Data Source & Attribution
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