Loading clinical trials...

Evaluation of Topical Chamomile Versus Topical Triamcinolone Acetonide in Management of Oral Lichen Planus | Clinical Trials | Clareo Health

UNKNOWNPHASE1

Evaluation of Topical Chamomile Versus Topical Triamcinolone Acetonide in Management of Oral Lichen Planus

NCT03793634•Cairo University

View on ClinicalTrials.gov

Summary

Using of herbal medications as topical chamomile which has antioxidant, anti-inflammatory and anticarcinogenesis effect with little side effects is the aim for the future treatment of OLP.

Detailed Description

Oral lichen planus (OLP) is a chronic inflammatory T cell mediated autoimmune disease that affects skin and any mucous membrane particularly oral mucosa.The patient complains of burning sensation, pain; interference with eating, swallowing and speech leading to worsening of quality of life.Oxidative stress plays a role in pathomechanism of OLP disease. Enzymatic and non- enzymatic anti-oxidants act as a physiological guard against reactive oxygen species (ROS) and cytokine-mediated toxicity.Herbal treatment is the aim of the future therapy.Chamomile has anti-oxidant , anti-inflammatory effect and accelerate healing.

Eligibility

Age

30 - 80 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Symptomatic OLP.
•Patients with no history of taking corticosteroids for the last 6 months.
•Patients who agree to take medication.
•Medically free

Exclusion Criteria

•Patients with oral lesions other than OLP.
•Lichenoid reaction .
•Pregnant females and lactation.
•Smokers

Key Dates

Start Date

January 15, 2019

Primary Completion Date

December 1, 2019

Completion Date

March 1, 2020

Last Updated

January 4, 2019

Enrollment

ESTIMATED participants

Conditions

Oral Lichen Planus

Interventions

topical chamomile

DRUG

Evaluation of Efficacy and Safety of add-on Tofacitinib in Patients With Oral Lichen Planus

NCT07131813

Oral Lichen Planus

View study

RECRUITING

SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography

NCT06321003

Oral Squamous Cell CarcinomaOral Potentially Malignant Disorder+10 more

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 4, 2019Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Evaluation of Topical Chamomile Versus Topical Triamcinolone Acetonide in Management of Oral Lichen Planus

Inclusion Criteria

Exclusion Criteria

Evaluation of Efficacy and Safety of add-on Tofacitinib in Patients With Oral Lichen Planus

SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography

Thyme Honey for Management of Oral Lichen Planus

Dual-light Antibacterial Photodynamic Therapy as an Adjunctive Treatment to Corticosteroid Treatment in OLP

Evaluation of Artificial Intelligence in Diagnosis and Risk Assessment of Oral Potentially Malignant Disorders

Relationship Between Oral Lichen Planus and Autoimmune Thyroid Diseases