Metformin and Systemic Inflammation in HIV

Inclusion Criteria

• •Both sexes,
• •Age ≥18 years of age
• •With a diagnosis of HIV-1 infection,
• •That they are receiving TARE for at least 12 months (time necessary to establish a stable reservoir),
• •Patients with undetectable viral load (\<40 copies / mL) for at least 12 months,
• •Have a CD4 + level\> 200 cells / μL,
• •That they do not have a diagnosis of co-infection with HCV or HBV,
• •Patients who do not have a severe alcohol intake (\<21 glasses / week in men and \<14 glasses / week in women),
• •Patients who do not use drugs during the last 90 days prior to the screening visit, or during the study,
• •Who wish to participate voluntarily in the study and give their written consent.