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In the everyday clinical practice the incidence of minor complications is approximately 15-20% of the total number of third molar removals. Alveolitis (dry socket syndrome) may arise in 30-40% of the surgical tooth removals. Several preventive approaches are known, such as the use of iodoform gauze, zink-oxide eugenol paste, platelet rich fibrin (PRF), different medicine containing pastes, like antibiotics containing, non-steroid pain killer containing, steroid containing, or the application of chlorhexidine gel and solutions. In the case of a manifest alveolitis these methods can be used as well. The aims of this research are: i) to identify the important pathogens which play role in the development of alveolitis (microbiological methods), ii) to analyze the in vitro effectivity of the different antiseptic materials in case of infections (inhibitory zones) iii) to compare the effectivity of different alveolitis preventive methods in a prospective clinical study, iv) to compare the different treatment options in alveolitis in a prospective clinical study.
Age
18 - 100 years
Sex
ALL
Healthy Volunteers
Yes
Department of Oral and Maxillofacial Surgery, University of Pécs
Pécs, Hungary
Start Date
September 1, 2018
Primary Completion Date
September 30, 2020
Completion Date
September 30, 2021
Last Updated
November 15, 2018
50
ESTIMATED participants
Iodoform
DRUG
Wound closure using sutures
OTHER
Chlorhexidine
DRUG
Lead Sponsor
University of Pecs
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