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The purpose of this study was to observe the therapeutic effect of near-infrared light irradiation on the treatment of acute spinal cord injury in humans, and whether it can promote the recovery of neurological function. Half of the patients underwent laminectomy and decompression surgery, and the other half of the patients were implanted with irradiated fibers for irradiation after surgery.
The annual incidence of spinal cord injury has increased year by year, and there is currently no effective treatment. Near-infrared light has been widely used in clinical medicine because of its bio-stimulating effect, convenient use, harmless to the body, easy to be accepted by patients, and convenient for clinical promotion. The near-infrared light biostimulation effect can enhance the activity of various enzymes, inhibit inflammatory cells, inhibit neuronal apoptosis, and promote nerve regeneration. It has been widely confirmed and widely used in the rehabilitation of central nervous system and peripheral nerve injury. However, the position of the spinal cord is deep, and the depth of illumination used by laser treatment equipment is generally difficult to reach. The implantable 360° scattering fiber the investigators developed was implanted in the surgical site together with the drainage tube for irradiation treatment without additional patient damage.
Age
20 - 70 years
Sex
ALL
Healthy Volunteers
No
Xijing Hospital
Xi'an, Shaanxi, China
Start Date
September 1, 2018
Primary Completion Date
June 30, 2019
Completion Date
December 30, 2019
Last Updated
August 22, 2018
60
ESTIMATED participants
Laminectomy
PROCEDURE
Spinal nerve laser therapeutic apparatus(Composed of 808-band fully automatic control laser device and implantable 360° scattering medical fiber)
DEVICE
Lead Sponsor
Xijing Hospital
NCT06521723
NCT05563103
NCT07386522
Data Source & Attribution
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