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Intestinal Microbial Diversity of Small Bowel Stoma Effluent and Colonic Feces of Children With Short Bowel Syndrome
Several studies suggested that dysbacteriosis usually happened in patients with intestinal failure (IF). However, differences of microbiota diversity in small intestine stoma effluents and colonic faeces were rarely studies. Thus this study is aimed to investigate the microbiota compositions and differences of output of small intestine stoma and colon in pediatric IF patients. Fecal samples from IF patients. Each patient received fistula closure in our centre and fecal samples from both small intestinal stoma and colon were collected. Fecal microbial compositions were determined by high-throughput sequencing.
Age
0 - 3 years
Sex
ALL
Healthy Volunteers
Yes
Shanghai Xinhua Hospital, affiliated to Shanghai Jiao Tong University, School of Medicine
Shanghai, China
Start Date
November 1, 2016
Primary Completion Date
December 15, 2019
Completion Date
June 1, 2020
Last Updated
February 15, 2019
60
ESTIMATED participants
Lead Sponsor
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Collaborators
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT05813535