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3M Cavilon Advanced Skin Protectant for the Prophylaxis of Radiation Dermatitis | Clinical Trials | Clareo Health

COMPLETED

3M Cavilon Advanced Skin Protectant for the Prophylaxis of Radiation Dermatitis

Assessment of 3M Cavilon Advanced Skin Protectant for the Prophylaxis of Radiation Dermatitis in Cancer Patients

NCT03546803•Mayo Clinic

Summary

This study observes a liquid skin protectant that is a polymeric-cyanoacrylate solution designed to protect intact or damaged skin due to radiation.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Age ≥ 18years.
•Patient has initial or recurrent disease
•Undergoing external beam radiotherapy at the Mayo Clinic Rochester campus Note: Patients who are undergoing concurrent chemotherapy are eligible
•Ability to complete questionnaire(s) by themselves or with assistance
•Provide informed written consent
•Willing to consent for photography of radiation field
•Available to return to Mayo Clinic in within 1 week post treatment for assessment (+/- 7 days).
•At risk for developing ≥ grade 2 dermatitis radiation as determined by treating Radiation Oncology clinician
•Biologic effective dose of \>42 Gy10 as calculated using the web site EQD2.com.

Exclusion Criteria

•Unable to provide informed consent
•Patients with active rash, pre-existing dermatitis, lupus or scleroderma within the treatment area that may make skin assessment for the study difficult
•Known history of developing an allergic reaction after using a product containing cyanoacrylate or acrylates
•Subject has a medical condition that in the opinion of the investigator should exclude him/her from participating in the study
•Subject has been enrolled in an investigational study where product was applied to the proposed study site within 30 days of the screening visit
•The skin area affected by radiation requires treatment with a concomitant medication or product (if applicable)

Locations (1)

Mayo Clinic

Rochester, Minnesota, United States

Key Dates

Start Date

February 19, 2018

Primary Completion Date

August 12, 2019

Completion Date

August 12, 2019

Last Updated

August 14, 2019

Enrollment

ACTUAL participants

Conditions

Radiation Dermatitis

Interventions

3M™ Cavilon™ Advanced Skin Protectant

OTHER

ROS-scavenging Amino Acid-derived Lipids for the Prevention and Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer

NCT07081074

Radiation Dermatitis

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RECRUITINGNA

StrataXRT vs Standard Clinical Practice for the Prevention of Acute Dermatitis in Head and Neck Cancers Patients

NCT03394417

Head and Neck CancersAcute Radiation Dermatitis

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 14, 2019Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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3M Cavilon Advanced Skin Protectant for the Prophylaxis of Radiation Dermatitis

Inclusion Criteria

Exclusion Criteria

ROS-scavenging Amino Acid-derived Lipids for the Prevention and Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer

StrataXRT vs Standard Clinical Practice for the Prevention of Acute Dermatitis in Head and Neck Cancers Patients

Study of KeraStat Cream for Radiation Dermatitis During Head and Neck Radiotherapy

A Reminder App to Reduce Radiation Dermatitis Rates in Patients with Head-and-Neck Cancer

Evaluation of the Effect of Nigella Sativa for the Prophylaxis to Radiation Induced Dermatitis in Breast Cancer Patients

Retrospective Cohort Study Comparing a Novel Gel Dressing vs SoC in the Treatment of Radiation Dermatitis