Safety and Efficacy of Remote Ischemic Conditioning in Patients With Spontaneous Intracerebral Hemorrhage

Exclusion Criteria

• •1. Definite evidence of secondary ICH, such as structural abnormality, brain tumor, thrombolytic drug, and other causes
• •2. A very high likelihood that the patient will die within the next 24 hours on the basis of clinical and/or radiological criteria
• •3. Already booked for surgical treatment
• •4. Life expectancy of less than 90 days due to comorbid conditions
• •5. Severe hematologic disease
• •6. Concurrent use of anticoagulation drugs including Warfarin, dabigatran, rivaroxaban.
• •7. Concurrent use of glibenclamide or nicorandil
• •8. Any soft tissue, orthopedic, or vascular injury, wounds or fractures in healthy upper limb which may pose a contraindication for application of RIC
• •9. Severe hepatic and renal dysfunction
• •10. Platelet count \<100×10\^9/L
• •11. Coagulopathy defined as INR,APTT,and PT beyond the upper limit of normal range
• •12. Known pregnancy, or positive pregnancy test, or breastfeeding
• •13. Patients being enrolled or having been enrolled in other clinical trial within 3 months prior to this clinical trial
• •14. A high likelihood that the patient will not adhere to the study treatment and follow up regimen
• •15. Patients unsuitable for enrollment in the clinical trial according to investigators decision making.