HIRREM for Stage 1 Primary Hypertension

Exclusion Criteria

• •Unable, unwilling, or incompetent to provide informed consent
• •Physically unable to come to the study visits, or to sit comfortably in a chair for up to two hours at a time
• •Weight is over the chair limit (285 pounds)
• •Known atherosclerotic cardiovascular disease
• •Cardiovascular risk score of ≥ 10% (per http://tools.acc.org/ASCVD-Risk-Estimator-Plus/#!/calculate/estimate/)
• •Prior diagnosis of stage 2 hypertension
• •Ongoing need for treatment of hypertension with medications
• •Known seizure disorder
• •Known or anticipated pregnancy
• •Severe hearing impairment (because the subject will be using headphones during the interventions)
• •Ongoing need for treatment with opiate, benzodiazepine, or anti-psychotic medications, anti-depressant medications such as SSRI, SNRI, or tricyclic, and sleep medications such as zolpidem or eszopiclone
• •Anticipated and ongoing use of recreational drugs, alcohol, or energy drinks
• •Ongoing need for treatment with thyroid medications
• •Are enrolled in another research study that includes an active intervention
• •Have previously received brainwave optimization (BWO), used a B2 or B2v2 wearable device, or previously participated in a HIRREM research study