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Prospective Evaluation of Minimally Invasive Facial Cosmetic Procedures Through Measured Volumetric Changes and Patient Reported Outcomes
A prospective, trial to quantitatively and qualitatively compare the dermal fillers for the treatment of age related aesthetic changes.
Dermal fillers have been approved for the treatment of age related aesthetic changes, including facial volume loss, and attenuation of the static and dynamic rhytid. Despite widespread use of volumizing fillers there is little data quantifying the subjective benefit of these minimally invasive treatments from the patient perspective. Furthermore, there is little data comparing the subjective benefit with true objective volumetric results. Such data will provide much needed information for patient counselling and treatment optimization for patient perceived outcomes. This study is to determine the patient reported outcomes of three different dermal fillers and establish the volumetric changes over 90 days. Screening will be performed during the patient's office visit. Approximately 100 patients will be enrolled. Patients will participate up to 90 days (Day 1, 14 days, 28 days, and 90 days).
Age
40 - 65 years
Sex
FEMALE
Healthy Volunteers
Yes
University of Pennsylvania Health System
Philadelphia, Pennsylvania, United States
Start Date
August 21, 2020
Primary Completion Date
February 28, 2024
Completion Date
May 29, 2024
Last Updated
September 27, 2024
101
ACTUAL participants
Restylane-L®
DRUG
Restylane-L® Lyft
DRUG
Restylane Silk®
DRUG
Lead Sponsor
University of Pennsylvania
Collaborators
NCT07261748
NCT05167864
Data Source & Attribution
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