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Single-center Prospective Randomized Controlled Study of the Three-port Laparoscopic Surgery Versus Conventional Laparoscopic Surgery for Colorectal Cancer
This study is designed to evaluate the short-term and long-term results after three-port laparoscopic surgery for colorectal cancer(TLSC) compared with conventional laparoscopic surgery for colorectal cancer(CLSC).
At present,surgical treatments is the main means to cure colorectal cancer(CRC).The use of four or more ports has been routine in most laparoscopic colorectal resections. However,the drawbacks are the need for added manpower, consisting of another assistant to provide counter-traction, as well as costs and the unaesthetic effects of additional ports. In order to minimize surgical trauma, improve cosmesis ,reduce manpower,single-incision laparoscopic surgery (SILS) is attracting increasing attention. But it is challenging and highly demanding techniques. Becoming proficient at three-port laparoscopic surgery can make the transition to SILS more nature.Few studies about three-port laparoscopic surgery for colorectal cancer(TLSC) have been reported currently.More studies, especially large-scale, randomized controlled trials are needed to establish the best indications for TLSC. This is a single-center, open-label, non-inferiority, randomized controlled trial. A total of 282 eligible patients will be randomly assigned to TLSC group and CLSC group at a 1:1 ratio. It will provide valuable clinical evidence for the objective assessment of the the feasibility, safety, and potential benefits of TLSC compared with CLSC.
Age
18 - 80 years
Sex
ALL
Healthy Volunteers
Yes
Ruijin Hospital
Shanghai, Shanghai Municipality, China
Start Date
March 25, 2018
Primary Completion Date
March 1, 2020
Completion Date
March 1, 2025
Last Updated
February 13, 2020
282
ESTIMATED participants
Three-port Laparoscopic Surgery
PROCEDURE
Conventional Laparoscopic Surgery
PROCEDURE
Lead Sponsor
Ruijin Hospital
NCT04704661
NCT06696768
Data Source & Attribution
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