Growth and Asymmetric diMethylArginine

Exclusion Criteria

• •Chronic disabling disease (ex: diabetes, severe asthma)
• •Evolving cancer
• •Severe psychiatric disorder (ex: autism, schizophrenia; severe depression)
• •Hypothalamic tumor (ex: craniopharyngioma)
• •Anamnesis of cranial irradiation
• •Overweight, obesity or thinness
• •Precocious puberty
• •Non-replacing therapy by glucocorticoids or sex steroids less than 1 month before the exploration
• •Anterior treatment by recombinant human GH
• •Other conditions, treatments or habits impacting arterial reactivity: acrocyanosis, cryoglobulinemia, beta adrenergic blocking habits, tobacco smoking or other drug addictions, dyslipidemia
• •Pregnancy or lactation
• •Acute infection less than three weeks before the investigation
• •Participation to a therapeutic protocol
• •Impossibility for the representatives of the parental authority to understand the objectives of the protocol
• •Absence of social security coverage. Refusal by the parents to sign the informed consent or oral refusal by the child to participate to the study