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A Phase 1 Open-Label Study to Evaluate the Pharmacokinetics of Filgotinib in Subjects With Impaired Hepatic Function
The primary objective of this study is to evaluate the pharmacokinetics (PK) of filgotinib and its metabolite, GS-829845, in participants with varying degrees of impaired hepatic function relative to matched, healthy controls.
Age
18 - 70 years
Sex
ALL
Healthy Volunteers
Yes
Clinical Pharmacology of Miami
Miami, Florida, United States
American Research Corporation at the Texas Liver Institute
San Antonio, Texas, United States
APEX GmbH
Munich, Germany
Auckland Clinical Studies Ltd.
Grafton, Auckland, New Zealand
Start Date
April 3, 2018
Primary Completion Date
August 9, 2018
Completion Date
August 9, 2018
Last Updated
January 15, 2021
20
ACTUAL participants
Filgotinib
DRUG
Lead Sponsor
Gilead Sciences
Collaborators
NCT06647069
NCT07484243
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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