Changes in PPV Induced by PLR Test to Predict Fluid Responsiveness in ICU

Inclusion Criteria

• •Mechanically ventilated patients
• •Patients in whom the physician decides to perform a fluid challenge based on the presence of one of the following criteria:
• •(1) systolic arterial pressure \<90 mmHg, mean arterial pressure \<65 mmHg, or the need for vasopressor infusion; (2) skin mottling; (3) urine output \<0.5 mL/Kg/h for more than or equal to 2 hours; (4) lactate concentrations \> 2 mmol/L
• •Patients in whom the physician decides to perform a PLR test to predict fluid responsiveness
• •Arterial catheter should be in place for invasive monitoring of arterial pressure and PPV
• •Age \<18 yrs
• •Pregnancy
• •Moribund patients
• •Risk of fluid loading induced pulmonary edema
• •Cardiac arrhythmias
• •Contraindication to perform PLR (intracranial hypertension, pelvic fractures)